Amphetamine

$375.00$9,600.00

IUPAC ID: 1-phenylpropan-2-amine
Drug class: CNS stimulant, anorectic
Duration of action: IR dosing: 3–6 hours; XR dosing: 8–12 hours
Onset of action: IR dosing: 30–60 minutes; XR dosing: 1.5–2 hours
Other names: α-methylphenethylamine
Metabolism: CYP2D6, DBH, FMO3

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Description

Medical Uses

Amphetamine is used to treat attention deficit hyperactivity disorder (ADHD), narcolepsy (a sleep disorder), and obesity, and is sometimes prescribed off-label for its past medical indications, particularly for depression and chronic pain. Long-term amphetamine exposure at sufficiently high doses in some animal species is known to produce abnormal dopamine system development or nerve damage, but, in humans with ADHD, pharmaceutical amphetamines, at therapeutic dosages, appear to improve brain development and nerve growth. Reviews of magnetic resonance imaging (MRI) studies suggest that long-term treatment with amphetamine decreases abnormalities in brain structure and function found in subjects with ADHD, and improves function in several parts of the brain, such as the right caudate nucleus of the basal ganglia.

Adverse Effects

Cardiovascular side effects can include hypertension or hypotension from a vasovagal responseRaynaud’s phenomenon (reduced blood flow to the hands and feet), and tachycardia (increased heart rate). Sexual side effects in males may include erectile dysfunction, frequent erections, or prolonged erections. Gastrointestinal side effects may include abdominal painconstipationdiarrhea, and nausea. Other potential physical side effects include appetite lossblurred visiondry mouthexcessive grinding of the teeth, nosebleed, profuse sweating, rhinitis medicamentosa (drug-induced nasal congestion), reduced seizure thresholdtics (a type of movement disorder), and weight loss. Dangerous physical side effects are rare at typical pharmaceutical doses.

Amphetamine

Additional information

Quantity

10g, 50g, 100g, 250g, 500g, 1000g

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