3,4-Methyl​enedioxy​methamphetamine (Mdma)


Formula: C₁₁H₁₅NO₂
Other names: 3,4-MDMA; Ecstasy (E, X, XTC); Molly; Mandy
Onset of action: 30–45 minutes (by mouth)
Duration of action: 4–6 hours
Metabolism: Liver, CYP450 extensively involved, including CYP2D6
Metabolites: MDA, HMMA, HMA, DHA, MDP2P, MDOH



Recreational Usage

34-methyl​enedioxy​methamphetamine-mdma or MDMA is often considered the drug of choice within the rave culture and is also used at clubs, festivals, and house parties. In the rave environment, the sensory effects of music and lighting are often highly synergistic with the drug. The psychedelic amphetamine quality of MDMA offers multiple appealing aspects to users in the rave setting. Some users enjoy the feeling of mass communion from the inhibition-reducing effects of the drug, while others use it as party fuel because of the drug’s stimulatory effects. MDMA is used less often than other stimulants, typically less than once per week.


MDMA is sometimes taken in conjunction with other psychoactive drugs such as LSDpsilocybin mushrooms, and ketamine, an act called “candy-flipping”.

Other Usages

Small doses of MDMA are used by some religious practitioners as an entheogen to enhance prayer or meditation. MDMA has been used as an adjunct to New Age spiritual practices.

Adverse Effects


Acute adverse effects are usually the result of high or multiple doses, although single dose toxicity can occur in susceptible individuals. The most serious short-term physical health risks of MDMA are hyperthermia and dehydration. Cases of life-threatening or fatal hyponatremia (excessively low sodium concentration in the blood) have developed in MDMA users attempting to prevent dehydration by consuming excessive amounts of water without replenishing electrolytes.

The immediate adverse effects of MDMA use can include:

  • Dehydration
  • Hyperthermia
  • Bruxism (grinding and clenching of the teeth)
  • Increased wakefulness or insomnia
  • Increased perspiration and sweating
  • Increased heart rate and blood pressure
  • Increased psychomotor activity
  • Loss of appetite
  • Nausea and vomiting
  • Diarrhea
  • Erectile dysfunction
  • Visual and auditory hallucinations (rarely)

Other adverse effects that may occur or persist for up to a week following cessation of moderate MDMA use include:


  • Trismus (lockjaw)
  • Loss of appetite
  • Insomnia
  • Tiredness or lethargy


  • Anxiety or paranoia
  • Depression
  • Irritability
  • Impulsiveness
  • Restlessness
  • Memory impairment
  • Anhedonia

Additional information


10g, 50g, 100g, 250g, 500g, 1000g


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