Unbelievable Manifest 3-HO-PCP (3-Hydroxyphencyclidine)

$250.00$5,300.00  /  0.01313 Ƀ

IUPAC Name: 3-(1-(piperidin-1-yl)cyclohexyl)phenol
Molecular Formula: C17H25NO
Molecular Mass: 259.39g/mol
CAS NO: 79295-51-5


3-Hydroxyphencyclidine [3-HO-PCP]

3-Hydroxyphencyclidine (3-HO-PCP) is a dissociative of the arylcyclohexylamine class related to phencyclidine (PCP) that has been sold online as a designer drug.

Very little research exists on the use and misuse of 3-HO-PCP.

A functional stimulant related to phenmetrazine. Effects similar to amphetamine, but longer and more focused. Observed as being relatively benign in low doses, but seems to cause worrying health effects for heavy users. Pain from insufflation is eye-wateringly intense, but short.

What is 3-Hydroxyphencyclidine

3-HO-PCP stands for 3-Hydroxyphencyclidine. It is a dissociative chemical that falls into the arylcyclohexylamine class. It is an NMDA receptor antagonist. 3-HO-PCP was first synthesized in 1978. It has been a favorite for research chemists for many years.

3-Hydroxyphencyclidine experiments typically yield findings of stimulation, sedation, physical euphoria, tactile enhancement, pain relief, changes in gravity perception, dis-inhibition, conceptual thinking, time distortion.

Increased music appreciation, thought connectivity, hallucinations, and perspective distortion. It is very potent so make sure that you follow all laboratory safety procedures if you experiment with it. 3-HO-PCP is a great addition to any lab.


3-HO-PCP acts as a high-affinity uncompetitive antagonist of the NMDA receptor via the dizocilpine (MK-801) site (Ki = 30 nM).[3][4] It has much higher affinity than PCP for this site (Ki = 250 nM, for comparison; 8-fold difference).[4]

The drug also has high affinity for the μ-opioid receptor (MOR) (Ki = 39–60 nM) in animal test subjects,[3][4][5][6] the κ-opioid receptor (KOR) (Ki = 140 nM),[5] and the sigma σ1 receptor (Ki = 42 nM; IC50 = 19 nM),[5][7][8][9] whereas it has only low affinity for the δ-opioid receptor .

The high affinity of 3-HO-PCP for opioid receptors is unique among arylcyclohexylamines and is in contrast to PCP, which has only very low affinity for the MOR (Ki = 11,000–26,000 nM; 282- to 433-fold difference) and the other opioid receptors.

Although it was hypothesized that 3-HO-PCP might be a metabolite of PCP in humans, there is no evidence that this is the case.[10][11]


3-HO-PCP is an arylcyclohexylamine.[3] Close analogues of 3-HO-PCP include PCP, 3-MeO-PCP, 4-MeO-PCP, 3-MeO-PCMo, and somewhat more distantly ketamine, methoxyketamine, 3-MeO-PCE, methoxetamine and dimetamine.[3]

Society and culture

Legal status

On October 18, 2012 the Advisory Council on the Misuse of Drugs in the United Kingdom released a report about methoxetamine, saying that the “harms of methoxetamine are commensurate with Class B of the Misuse of Drugs Act (1971).

The report went on to suggest that all analogues of MXE should also become class B drugs and suggested a catch-all clause covering both existing and unresearched arylcyclohexamines, including 3-HO-PCP.[12]

3-HO-PCP is banned in Sweden[13][14] and Switzerland.[15]

Where to buy 3-HO-PCP?

3-HO-PCP can be purchase from  We offer high-quality 3-HO-PCP for sale, typically in powder form. However, if you would like a different form, then feel free to contact us to let us know because we often have different forms available.

You must be at least 18 years old to buy 3-HO-PCP from us and be in full legal compliance with the research chemical laws of your country.

NOTE; The 3-HO-PCP is not intended for human or animal consumption. It is only intended for research purposes.

Buy 3-Hydroxyphencyclidine [3-HO-PCP]



3-Hydroxyphencyclidine [3-HO-PCP]

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3-HO-PCP Chemical

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Buy 3-Hydroxyphencyclidine [3-HO-PCP]

3-HO-PCP (3-hydroxyphencyclidine) is a synthetic dissociative of the arylcyclohexylamine class. The structure of 3-HO-PCP comprises cyclohexane, a six-member saturated ring, and is bonded to two additional rings at R1.

One of these rings is a piperidine ring, a nitrogenous six member ring, bonded at its nitrogen group. The other ring is an aromatic phenyl ring, substituted at R3 with a hydroxy group.

3-HO-PCP is a structural analogue of PCP and a homolog 3-MeO-PCP.

3-HO-PCP is sold for research purposes only and is not be utilized for any other purposes, including, but not limited to, in vivo diagnostic purposes, in foods, in drugs, in medicinal devices, and/or cosmetics for humans and/or animals.

Prior to ordering, please make certain that you are properly equipped for research chemicals and that your work area is well-ventilated.

You must be 18 or more years old to order this product.

Effects of 3-Hydroxyphencyclidine [3-HO-PCP]

Increased energy/alertness, Decreased need for sleep, Increased sociability, mood lift, increase sexuality, Excessive talking, Decreased appetite, Weight loss, Sweating, Distrubed sleep patterns, Bruxia, Visual and audiotory hallucinations itchiness, agressiveness, moodiness.


Additional information


10g, 50g, 100g, 250g, 500g, 1000g


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